ea0034p272 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2014
Hazlehurst Jonathan
, Armstrong Matthew
, Hodgkiss Jayne
, Crowley Rachel
, Geberhiwot Tarekegn
, Newsome Phillip
, Tomlinson Jeremy
Alstrom syndrome is an autosomal recessive ciliopathy that is characterised by increased body mass index, type 2 diabetes, retinal dystrophy, sensorineural hearing loss, cardiac fibrosis, and chronic kidney disease. Non-alcoholic fatty liver disease (NAFLD) in Alstrom patients ranges from simple steatosis, steatohepatitis and ultimately to fibrosis and cirrhosis. Nafld fibrosis score (http://nalfdscore.com/), enhanced liver fibrosis (ELF)-panel blood tests and Fibroscans are n...